THE IMMUNE RESPONSE AGAINST RABIES VIRUS AMONG CANINE DONORS IN A ROMANIAN BLOOD BANK

Authors

  • Teodor-Stefan Ionescu Faculty of Veterinary Medicine, University of Agronomic Science and Veterinary Medicine of Bucharest
  • Marius Dan Faculty of Veterinary Medicine, University of Agronomic Science and Veterinary Medicine of Bucharest
  • Dragos Cobzariu Faculty of Veterinary Medicine, University of Agronomic Science and Veterinary Medicine of Bucharest
  • Stelian Baraitareanu Faculty of Veterinary Medicine, University of Agronomic Science and Veterinary Medicine of Bucharest
  • Doina Danes Faculty of Veterinary Medicine, University of Agronomic Science and Veterinary Medicine of Bucharest

DOI:

https://doi.org/10.12955/pmp.v2.172

Keywords:

blood transfusion, blood donation, canine blood bank, ELISA OD, rabies

Abstract

INTRODUCTION: Seventy-six samples were collected from sixteen canine blood donors at every blood donation performed in accord with the canine donor selection guidelines. Statistical analysis of ELISA OD values revealed no significant variation of anti-rabies antibodies values during repeat donations. Our results support the statement that blood donation does not affect the immune status of donors.

OBJECTIVES: The study aimed to assess the immune status against rabies among the canine blood donors in a Romanian canine blood bank

METHODS: Serum samples (n=76) were collected from pet owned dogs (n=16) recorded in the blood bank register of a Romanian blood bank were performed with the immunological status of the investigated canine blood donors was evaluated using the indirect ELISA commercial kit PLATELIA RABIES II (BIO-RAD, France) as per the manufacturer's instructions

RESULTS: The overall picture of ELISA OD results revealed non-significant variation between and within D1-D6 groups of values (p>0.05, F<Fcrit).

CONCLUSION: The next studies topic would be to compare the results provided by the ELISA technology with FAVN.

References

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Published

2021-10-24

How to Cite

Ionescu, T.-S. ., Dan, M. ., Cobzariu, D. ., Baraitareanu, S. ., & Danes, D. . (2021). THE IMMUNE RESPONSE AGAINST RABIES VIRUS AMONG CANINE DONORS IN A ROMANIAN BLOOD BANK. Proceedings of CBU in Medicine and Pharmacy, 2, 53-59. https://doi.org/10.12955/pmp.v2.172