eRESEARCH IN THE DEGREE OF ADHERENCE BY ASTHMA PATIENTS – A PILOT STUDY

Authors

  • Anna Todorova Medical University Varna, Faculty of Pharmacy, Department of Organization and Economics of Pharmacy, Varna
  • Antoaneta Tsvetkova Medical University Varna, Training sector "Assistant Pharmacist" Medical College, Varna
  • Silvia Mihaylova Medical University Varna, Training sector "Assistant Pharmacist" Medical College, Varna

DOI:

https://doi.org/10.12955/pmp.v2.191

Keywords:

asthma, adherence, Morisky test

Abstract

Introduction: Non-adherence to treatment is a global issue which in recent years has reached epidemic proportions. The WHO has reported that treatment adherence in chronic patients is 50% in developed countries on average. According to data from the Association of Bulgarians with Bronchial Asthma (ABBA) the percentage of asthma patients who are not regularly treated is the highest compared with other chronic diseases. Non-adherence to treatment not just influences the patient’s quality of life but increases the health care costs in society.

Objectives: The aim of this study is to analyse the degree of adherence to prescribed treatment in asthma patients.

Methods: An anonymous survey was made among 50 outpatients with asthma using an adapted survey card consisting of two parts: a questionnaire that collects information about the demographic profile of the patient (gender, age, educational background, etc) and a validated tool, the Morisky test, which is a questionnaire that defines the degree of treatment adherence.

Results: The results from the Morisky test (Morisky coefficient 2.22) showed a mean degree of adherence both for the whole sample and for men and women separately, with a minimal difference of 0.01 in favour of men (Morisky coefficient 2.24 in men and 2.23 in women).

Conclusions: The studied asthma patients show unsatisfactory adherence to the prescribed treatment. The mean degree of adherence reported in the study indicates the need for educating patients, monitoring and collaboration among doctors, patients, pharmacists and other healthcare professionals.

References

De Smet BD, Erickson SR, Kirking DM , et al. (2006) Self-reported adherence in patients with asthma. Ann Pharmacother. 40(3):414-20. doi: 10.1345/aph.1G475

Foden J, Hand CH. (2008) Does use of a corticosteroid/long-acting beta-agonist combination inhaler increase adherence to inhaled corticosteroids? Prim Care Respir J; 17(4):246-7 doi: 10.3132/pcrj.2008.00051

Gaude GS, (2011) Factors Affecting non-adherence in Bronchial Asthma and Impact of Health Education. Indian J Allergy Asthma Immunol.; 25(1):1-8

Gillissen, A., (2007) Patient’s adherence in asthma. J Phys Pharm., 58 Suppl 5(Pt 1):205-22

GINA (2017) Global Strategy for Asthma Management and Prevention 2017 (update), available at: www.ginasthma.org

GINA (2019) Global strategy for asthma management and prevention, thttps://ginasthma.org/wp-content/uploads/2019/06/GINA-2019-main-report-June-2019-wms.pdf

Lavorini F. (2014) Inhaled drug delivery in the hands of the patient. J Aerosol Med Pulm Drug Deliv; 27(6):414–418. doi: 10.1089/jamp.2014.1132

Lindberg M., Ekstroem T., Moeller M. et al. (2001) Asthma care and factors affecting medication compliance: the patient’s point of view. International Journal for Quality in Health Care; 13(5):375–383 doi: 10.1093/intqhc/13.5.375.

Mäkelä MJ, Backer V, Hedegaard M, Larsson K. (2013) Adherence to inhaled therapies, health outcomes and costs in patients with asthma and COPD. Respir Med. 107(10):1481-90 doi: 10.1016/j.rmed.2013.04.005

Mitkova Z, Tashkov K, Dimitrova M, Manova M, (2017) Influence of the therapeutic regime on the compliance with the therapy in patients with chronic diseases in Bulgaria, Social Medicine, 2 (3); 29-32.

Morisky Medication-Taking Adherence Scale-MMAS (4-item) https://www.hal.inserm.fr/inserm-00663888/file/1472-6874-10-26-S2.PDF достъпено на 10.03.2021

Newman S. (2014) Improving inhaler technique, adherence to therapy and the precision of dosing: major challenges for pulmonary drug delivery. Expert Opin Drug Deliv.; 11(3):365–378. doi: 10.1517/17425247.2014.873402

Pearce C. J., Fleming L. (2018). Adherence to medication in children and adolescents with asthma: methods for monitoring and intervention. Expert review of clinical immunology; 14(12), 1055–1063 https://doi.org/10.1080/1744666X.2018.1532290

Petkova E., Popov D. (2015) Compliance and adherence to therapy in bronchial asthma. Vol. 5 (33) https://inspiro-bg.com/komplayans-i-pridarzhane-kam-terapiyata-pri-bronhialna-astma/, accessed on 30.03.2021

Price D., Lee A., Sims E. et al. (2013) Characteristics of patients preferring once-daily controller therapy for asthma and COPD: a retrospective cohort study. PrimCareRespirJ 22(2):161-168 doi: 10.4104/pcrj.2013.00017

Rand CS, Wise RA. (1994) Measuring adherence to asthma medication regimens. Am J Respir Crit Care Med.;149(2 Pt 2):S69-76; discussion S77-8. doi: 10.1164/ajrccm/149.2_Pt_2.S69.

Sabaté E. (2003) Adherence to Long-term Therapies: Evidence for Action. World Health Organization. Geneva; 1-194

Small M. et al., (2011) Importance of inhaler-device satisfaction in asthma treatment: Real-world observations of physician-observed compliance and clinical/patient-reported outcomes, Advances in Therapy 28(3):202-212 doi: 10.1007/s12325-010-0108-4

Stoloff SW, Stempel DA, Meyer J, Stanford RH, Carranza Rosenzweig JR. (2004) Improved refill persistence with fluticasone propionate and salmeterol in a single inhaler compared with other controller therapies. J Allergy Clin Immunol.; 113(2):245-51 DOI: 10.1016/j.jaci.2003.10.011

Thomas M, Price D, Chrystyn H, Lloyd A, Williams AE, von Ziegenweidt J. (2009) Inhaled corticosteroids for asthma: impact of practice level device switching on asthma control. BMC Pulm Med; 9:13 https://doi.org/10.1186/1471-2466-9-1

Downloads

Published

2021-10-24

How to Cite

Todorova, A. ., Tsvetkova, A. ., & Mihaylova, S. . (2021). eRESEARCH IN THE DEGREE OF ADHERENCE BY ASTHMA PATIENTS – A PILOT STUDY. Proceedings of CBU in Medicine and Pharmacy, 2, 168-173. https://doi.org/10.12955/pmp.v2.191